- Born: 9 August 1970, New York, New York, United States
- Height: 1.88 m
- Spouse: Cristina Greeven Cuomo (m. 2001)
- Children: Bella Cuomo, Carolina Regina Cuomo, Mario Cuomo
- Siblings: Andrew Cuomo, Margaret I. Cuomo, Maria Cuomo Cole, Madeline Cuomo
Cuomo is the brother of New York Governor Andrew Cuomo and son of the late New York Governor Mario Cuomo.