Rare genetic changes behind severe obesity | Dr Tessa Cacciottolo

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  • Dr Cacciottolo’s research focuses on cellular mechanisms which are disrupted in people with severe obesity due to rare genetic mutations.

    In this short expert talk, ‘Rare variants in Steroid Receptor Coactivator (SRC-1) associated with severe obesity’, Dr Cacciottolo explains her work on the homeostatic mechanisms regulating body weight. In particular, she is using mouse models to research rare genetic changes affecting how the hormone leptin functions within cells, and so consequently how the body to suppress appetite after eating.

    Dr Tessa Cacciottolo is a Wellcome Trust Clinical Research Fellow at the Wellcome-MRC Institute of Metabolic Science, University of Cambridge.

    Our Clinical Academics in Training Annual Conference, or CATAC, offers early career researchers the chance to present work and receive feedback from senior panelists in a truly interdisciplinary setting. The conference gives clinical academics the chance to meet people from all areas of biomedical science, and share ideas from many different perspectives.

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