U.K. Says Those With Severe Allergy Shouldn’t Get Pfizer Shot

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  • Bloomberg Quicktake: Now published this video item, entitled “U.K. Says Those With Severe Allergy Shouldn’t Get Pfizer Shot” – below is their description.

    People with a significant history of allergies should not currently receive the Covid-19 vaccine from Pfizer Inc. and BioNTech SE, the U.K.’s National Health Service said, after two people experienced reactions from the shots.

    The warning came a day after the U.K. became the first western nation to begin a Covid vaccination program, following approval of the shot last week by the Medicines and Healthcare Products Regulatory Agency. Thousands of people received vaccinations on Tuesday, according to the NHS.

    “As is common with new vaccines, the MHRA have advised on a precautionary basis that people with a significant history of allergic reactions do not receive this vaccination,” Stephen Powis, national medical director for the NHS in England, said in a statement.

    June Raine, chief executive of the MHRA, said her team looked at two case reports of allergic reactions on Tuesday evening. Both of the people, staff members of the NHS, are recovering well.

    “We know from the very extensive clinical trials that this wasn’t a feature, that if we need to strengthen our advice now that we’ve had this experience in the vulnerable populations, we get that advice to the field immediately,” Raine told a panel of lawmakers.

    Pfizer and BioNTech said they’re supporting the MHRA in its investigation.

    The U.K. agency had already warned in its prescribing information that people who are allergic to any ingredients in the vaccine shouldn’t take it. Patients with a history of severe adverse reactions to a vaccine or severe allergic reactions to any component of the treatment were excluded from participating in the large study run by the companies before approval.

    “In the pivotal phase 3 clinical trial, this vaccine was generally well tolerated with no serious safety concerns reported by the independent data monitoring committee,” the companies said in a statement.

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    In This Story: Allergy

    Allergies are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, a runny nose, shortness of breath, or swelling.

    Common allergens include pollen and certain foods. Metals and other substances may also cause problems. Food, insect stings, and medications are common causes of severe reactions. Their development is due to both genetic and environmental factors.

    Treatments for allergies include the avoidance of known allergens and the use of medications such as steroids and antihistamines. In severe reactions injectable adrenaline (epinephrine) is recommended.

    Allergies are common. In the developed world, about 20% of people are affected by allergic rhinitis, about 6% of people have at least one food allergy, and about 20% have atopic dermatitis at some point in time. Depending on the country about 1–18% of people have asthma. Anaphylaxis occurs in between 0.05–2% of people.

    Source: Wikipedia

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